Search for Cheap Deals onSpa Resort Hotels in St. Charles
Check Last Minute St. Charles Hotel Deals
You choose what matters — star rating, location, amenities.
We pick the perfect hotel, packed with all your must-haves.
Your hotel is revealed right after booking, and you save up to 60%!
Featured St. Charles Resorts & Hotels with Spas
Hampton Inn St. Charles St. Peters
3720 W Clay St, St. Charles, MO
Fully refundableReserve now, pay when you stay
Book a stay at this golf hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 4.5-star luxury hotel in St. Charles. Enjoy an outdoor pool, a full-service spa, and 5 restaurants. Our guests praise the helpful staff and the ...
Research Park Inn St Louis West – Chesterfield
32 Research Park Circle, St. Charles, MO
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Embassy Suites by Hilton St. Louis St. Charles
2 Convention Center Plz, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 3.5-star business-friendly hotel in St. Charles. Enjoy free breakfast, free parking, and a free area shuttle. Our guests praise the breakfast and ...
Country Inn & Suites by Radisson, St. Charles, MO
1190 S Main St, St. Charles, MO
Fully refundable
Book a stay at this business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
Drury Plaza Hotel St. Louis St. Charles
380 Mulholland Drive, St. Charles, MO
Fully refundableReserve now, pay when you stay
Stay at this 3-star business-friendly hotel in St. Charles. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels by Star Rating
St. Charles Neighborhoods
Top Points of Interests in St. Charles
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Katy Trail
- Hotels near Fast Lane Classic Cars
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near Missouri Bluffs Golf Course
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Jaycee Park
- Hotels near St. Louis Union Station
- Hotels near Busch Stadium
- Hotels near Gateway Arch
- Hotels near St. Louis Zoo
- Hotels near Six Flags St. Louis
- Hotels near Enterprise Center
- Hotels near Washington University in St. Louis
- Hotels near Forest Park
Cities near St. Charles
- Maryland Heights Hotels (6.33 mi)
- Chesterfield Hotels (9.49 mi)
- Collinsville Hotels (28.73 mi)
- Innsbrook Hotels (29.82 mi)
- St. Peters Hotels (6.7 mi)
- O'Fallon Hotels (11 mi)
- Wentzville Hotels (19.2 mi)
- Edwardsville Hotels (27.79 mi)
- Bridgeton Hotels (4.85 mi)
- Fenton Hotels (19.25 mi)
- East St. Louis Hotels (22.41 mi)
- Alton Hotels (18.27 mi)
- Grafton Hotels (13.05 mi)
- Arnold Hotels (25.37 mi)
- Ozarks Hotels (156.82 mi)
- Eureka Hotels (20.94 mi)
- Kirkwood Hotels (14.96 mi)
- Richmond Heights Hotels (14.6 mi)
- Washington Hotels (31.97 mi)
- Hazelwood Hotels (6.19 mi)
Car Rentals Near St. Charles
- Car rentals in Maryland Heights
- Car rentals in Chesterfield
- Car rentals in Collinsville
- Car rentals in Innsbrook
- Car rentals in St. Peters
- Car rentals in O'Fallon
- Car rentals in Wentzville
- Car rentals in Edwardsville
- Car rentals in Bridgeton
- Car rentals in Fenton
- Car rentals in East St. Louis
- Car rentals in Alton
- Car rentals in Grafton
- Car rentals in Arnold
- Car rentals in Ozarks
- Car rentals in Eureka
Top Spa Resort Destinations
- Annapolis Spa Hotels
- Ottawa Valley Spa Hotels
- Tallahassee Spa Hotels
- Appalachian Mountains Spa Hotels
- Corpus Christi Spa Hotels
- Raleigh Spa Hotels
- Syracuse Spa Hotels
- Chattanooga Spa Hotels
- Grand Canyon Spa Hotels
- Toledo Spa Hotels
- Edmonton Spa Hotels
- El Paso Spa Hotels
- Omaha Spa Hotels
- Cincinnati Spa Hotels
- Fargo Spa Hotels
- Des Moines Spa Hotels
- Dayton Spa Hotels
- Flagstaff Spa Hotels
- Little Rock Spa Hotels
- Waco Spa Hotels