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Have you been telling yourself, “2025 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Antofagasta Region is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Antofagasta Region that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Antofagasta Region? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Antofagasta Region by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Antofagasta Region. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from to .
  • Duration: Want to get to Antofagasta Region as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Antofagasta Region today and get going.

Last Minute Hotel Deals in Antofagasta Region

Diego de Almagro San Pedro de Atacama

Diego de Almagro San Pedro de Atacama

3 out of 5
Toconao 460, San Pedro de Atacama, Antofagasta
The price is $117 per night from Apr 24 to Apr 25
$117
includes taxes & fees
Apr 24 - Apr 25
Stay at this 3-star hotel in San Pedro de Atacama. Enjoy free breakfast, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
8/10 Very Good! (283 reviews)
Great location
"Perfectly nice place to stay. Very good value. Amazing location just metres from centre of San Pedro. Decent pool area. Breakfast was nice. Room was basic, cosy and clean. We only booked the day before so no complaints really. Stayed for 3 nights. If I was staying longer I would need a bigger room. ..."

Reviewed on Mar 27, 2025

Diego de Almagro San Pedro de Atacama
Park Hotel Calama

Park Hotel Calama

3.5 out of 5
Alcalde Jose Lira 1392, Calama, Antofagasta
The price is $70 per night from Apr 24 to Apr 25
$70
includes taxes & fees
Apr 24 - Apr 25
Stay at this 3.5-star business-friendly hotel in Calama. Enjoy free breakfast, free WiFi, and free parking. Popular attractions San Juan Bautista Cathedral and ...
8/10 Very Good! (251 reviews)
"great staff, awesome food, clean and convenient"

Reviewed on Jan 25, 2025

Park Hotel Calama
Holiday Inn Express Antofagasta by IHG

Holiday Inn Express Antofagasta by IHG

3.5 out of 5
Ave. Grecia 1490, Antofagasta, Antofagasta
The price is $62 per night from May 18 to May 19
$62
includes taxes & fees
May 18 - May 19
Stay at this 3.5-star business-friendly hotel in Antofagasta. Enjoy free breakfast, free WiFi, and free parking. Popular attractions El Tatio and Antofagasta ...
8.8/10 Excellent! (311 reviews)
Recommend!
"Very comfortable hotel with good amenities and conveniences. Many restaurants are nearby. The room was spacious and it is definitely a good value for the money"

Reviewed on Mar 6, 2025

Holiday Inn Express Antofagasta by IHG
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Hotel La Casa de Don Tomas

Hotel La Casa de Don Tomas

3 out of 5
Calle Tocopilla Sitio 18, San Pedro de Atacama
The price is $210 per night from Apr 23 to Apr 24
$210
includes taxes & fees
Apr 23 - Apr 24
Stay at this 3-star hotel in San Pedro de Atacama. Enjoy free breakfast, free WiFi, and 2 restaurants. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (328 reviews)
"The staff are excellent , both helpful and friendly. The restaurant is far above what you would expect in such an outpost . The location is a short walk from the centre, and it allows it to sit like an oasis of calm if that’s what your looking for.. we all found it relaxing after taking tours off ..."

Reviewed on Mar 26, 2025

Hotel La Casa de Don Tomas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.