Cheap Rental Car Deals in Florida Keys
24/7 Customer Service
Up to 60% savings*
Low price guarantee
Hot Rate® Car rentals in Florida Keys
Today's top deal

Midsize SUV

Compact

Midsize

Premium

Minivan

Standard SUV

Luxury

Standard Elite SUV
Hot Rate® Sedan Car rentals in Florida Keys
Today's top deal

Standard

Compact

Midsize

Premium
Hot Rate® SUV Car rentals in Florida Keys
Today's top deal

Standard SUV

Standard Elite SUV

Full Size SUV

Luxury Elite SUV
More rental deals in Florida Keys

Compact


Midsize


Special Car

Alamo Car Rentals in Florida Keys

Compact SUV


Midsize SUV


Special Car


Full Size

Find Florida Keys Car Rentals
Hotwire.com makes it easy for you to book your next Florida Keys car rental. We work with the best car rental companies in Florida Keys, bringing you discount car rental rates and a wide variety of car rental classes including economy, compact, midsize, full-size, convertible, van, luxury, full size and SUV rentals. Our partner car rental companies in Florida Keys offer different pick-up and drop-off options. If you are ready to book your Florida Keys car rental, follow the links on this page to view more information and details on your next car rental.
Hotwire offers a wide selection of rental cars in Florida Keys to meet nearly every need. If you need any special equipment, like a child seat or ski rack, let us know and we will forward your request on to the rental car company. And what’s more, when you choose to rent a car from one of our Florida Keys airport car rental partners you’ll be dealing with a rental car company that has made a special commitment to provide Hotwire customers with great customer service, a wide choice of top quality cars, and competitive total pricing.
Hotwire offers many Florida Keys rental cars pick up locations
Find the best place to get your Florida Keys airport rental cars by searching tons of pickup locations with Hotwire
- Popular Car Rental Deals by Destination
- Popular Car Suppliers
- Car Rentals Near Top National Parks
- Popular Airport Car Rentals
- Top Nearby Airport Car Rentals
- Top Package Deals for Nearby Neighborhoods
- Top Package Deals
- Flight + Hotel Packages For Popular Attractions
- Cross Country Flight + Package Deals
Car Rental Deals in Florida Keys
- Car rentals in Las Vegas
- Car rentals in New York
- Car rentals in Orlando
- Car rentals in London
- Car rentals in Paris
- Car rentals in Cancun
- Car rentals in Miami
- Car rentals in Los Angeles
- Car rentals in Rome
- Car rentals in Punta Cana
- Car rentals in Riviera Maya
- Car rentals in Barcelona
- Car rentals in San Francisco
- Car rentals in San Diego County
- Car rentals in Oahu
- Car rentals in Chicago
Popular Airport Car Rental Destinations in Florida Keys
- Dallas-Fort Worth International Airport (DFW)
- Boston Logan Airport (BOS)
- Cincinnati-Northern Kentucky International Airport (CVG)
- Denver International Airport (DEN)
- Hartsfield-Jackson Airport (ATL)
- Las Vegas McCarran Intl Airport (LAS)
- Dulles Airport (IAD)
- Los Angeles International Airport (LAX)
- John F. Kennedy International Airport (JFK)
- La Guardia Airport (LGA)
- O'Hare International Airport (ORD)
- Philadelphia Airport (PHL)
- Minneapolis-St. Paul International Airport (MSP)
- Orlando Airport (MCO)
- Portland International Airport (PDX)
- New Orleans Airport (MSY)
- SeaTac Airport (SEA)
- Sky Harbor Airport (PHX)
- Toronto Airport (YYZ)
- San Francisco International Airport (SFO)
Packages for top Florida Keys Neighborhoods
Packages In and Around United States of America
Flight + Hotel Packages to Florida Keys's Most Popular Tourist Attractions
- Duval Street Vacations
- Mallory Square Vacations
- Smathers Beach Vacations
- Southernmost Point Vacations
- Sombrero Beach Vacations
- Ernest Hemingway Home and Museum Vacations
- South Beach Vacations
- Key West Golf Club Vacations
- Jimmy Johnson's Big Chill Vacations
- John Pennekamp Coral Reef State Park Vacations
Flight + Hotel to Destinations across the Country
Car Rental Locations of Florida Keys
- Car rentals in Miami Beach
- Car rentals in Key West
- Car rentals in Marathon
- Car rentals in Key Largo
- Car rentals in Islamorada
- Car rentals in Doral
- Car rentals in Coral Gables
- Car rentals in Homestead
- Car rentals in Miami Springs
- Car rentals in Key Biscayne
- Car rentals in Big Pine Key
- Car rentals in Tavernier
- Car rentals in Hialeah
- Car rentals in Cudjoe Key
- Car rentals in Florida City
- Car rentals in Little Torch Key
- Car rentals in Sugarloaf Key
- Car rentals in Long Key
- Car rentals in Key Colony Beach
- Car rentals in South Florida
- Car rentals in Gulf Coast
- Car rentals in Cutler Bay
- Car rentals in Summerland Key
- Car rentals in Duck Key
- Car rentals in Rock Harbor
- Car rentals in Ramrod Key
- Car rentals in Big Coppitt Key
- Car rentals in Lower Florida Keys
- Car rentals in Pinecrest
- Car rentals in Stock Island
- Car rentals in Layton
- Car rentals in Coupon Bight Aquatic Preserve
- Car rentals in Flamingo
- Car rentals in Southeastern United States
- Car rentals in West Miami
- Car rentals in Southeast Florida
- Car rentals in Conch Key
- Car rentals in Princeton
- Car rentals in Bahia Honda Key
- Car rentals in Gulf of Mexico
Top Florida Keys Hotels
- Cheeca Lodge & Spa
- Isla Bella Beach Resort & Spa
- Baker's Cay Resort Key Largo, Curio Collection by Hilton
- Chesapeake Beach Resort
- Faro Blanco Resort & Yacht Club
- Playa Largo Resort & Spa, Autograph Collection
- Bayside Inn Key Largo
- Islander Resort
- Lime Tree Bay Resort
- Aqua Lodge Rentals At Coconut Cay
- The Pelican Key Largo Cottages
- Tranquility Bay Beachfront Hotel and Resort
Visiting Florida Keys
*Savings are based on actual Hot Rate® car rentals made from airport pick-up locations as compared with the lowest published rates found on leading retail travel sites. Prices are dynamic and vary based on the booking date and length of the car rental. There is no guarantee these savings or rates will be in effect at the time of your search. Availability is limited. Hot Rate® cars are different from retail rates. With Hot Rate® cars you enter the location, date, and car class. The car rental company is revealed only after booking. All bookings are final.