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Independent in Cape Girardeau

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Tonight May 17 - May 18This weekend May 17 - May 19

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Featured Cape Girardeau Independent

Hotel 7 Inn Anna
Hotel 7 Inn Anna
2.5 out of 5
100 Richview Dr, Anna, IL
Book a stay at this business-friendly hotel in Anna. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Anna City Park and Lincoln Heritage ...
Hotel 7 Inn Anna
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
2.5 out of 5
3265 William St, Cape Girardeau, MO
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the ...
Auburn Place Hotel And Suites
Town House Inn
Town House Inn
2.5 out of 5
517 E Jackson Blvd, Jackson, MO
Stay at this motel in Jackson. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Litz Park and Lazy L Safari Park are located ...
Town House Inn
Town House Inn Cape Giradreau
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
Stay at this motel in Cape Girardeau. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Cape Splash Family Aquatic Center and Show ...
Town House Inn Cape Giradreau
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and Hotel
3 out of 5
301 1st St, Marble Hill, MO
Stay at this 3-star hotel in Marble Hill. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews.
EC Reed's Mercantile and Hotel
Davie School Inn
Davie School Inn
4 out of 5
300 Freeman St, Anna, IL
Stay at this 4-star business-friendly B&B in Anna. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Anna City Park and Lincoln Heritage ...
Davie School Inn
Regency Inn
Regency Inn
2 out of 5
128 CHEEKWOOD LN, Ullin, IL
Stay at this hotel in Ullin. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Ullin City Hall and Limekin Springs Trail Trailhead ...
Regency Inn
Makanda Inn
Makanda Inn
3.5 out of 5
855 Old Lower Cobden Road, Makanda, IL
Stay at this 3.5-star B&B in Makanda. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Arrowwood Trail Trailhead and Giant City ...
Makanda Inn
Giant City Lodge
Giant City Lodge
2.5 out of 5
460 Giant City Lodge Road, Cobden, IL
Stay at this lodge in Cobden. Enjoy free parking, an outdoor pool, and breakfast (surcharge). Popular attractions Indian Creek Trail Trailhead and Giant City ...
Giant City Lodge
Oak Grove Cabins
Oak Grove Cabins
3 out of 5
413 Oak Grove Rd, Makanda, IL
Stay at this 3-star cabin in Makanda. Enjoy free parking, balconies, and satellite TV channels. Popular attractions Stone Creek Golf Club and Resort and Cave ...
Oak Grove Cabins
Kite Hill Vineyards Bed & Breakfast
Kite Hill Vineyards Bed & Breakfast
3 out of 5
83 Kite Hill Road, Carbondale, IL
Stay at this 3-star B&B in Carbondale. Enjoy free breakfast, free parking, and an attached winery. Popular attractions Kite Hill Vineyards and Cave Hollow Trailhead ...
Kite Hill Vineyards Bed & Breakfast
Best Western Plus Jackson Cape Girardeau
Best Western Plus Jackson Cape Girardeau
2 out of 5
3003 S Old Orchard Rd, Jackson, MO
Stay at this hotel in Jackson. Enjoy free parking, a fitness center, and an outdoor pool. Popular attractions Cape Girardeau Conservation Nature Center and Lazy ...
Best Western Plus Jackson Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Independent hotels in Cape Girardeau

You’ve already taken the guesswork out of your next vacation. You know you want a Independent hotel in Cape Girardeau. What can you say? You like their style, they’re in a good part of Cape Girardeau, and they never let you down. New bar in town? You’re the first one to check it out. Spiciest item on the menu? You can take the heat. But even the best gamblers hedge their bets. No matter how crazy good your trip is, you want something familiar waiting for you at the end of the day.

All in a name

We all have favorites. There’s nothing wrong with knowing what you like. You like to stay at Independent near , Cape Girardeau to do the tourist thing (because sometimes it is fun) and then hit up the places that aren’t on the map. And no matter what fun you get into, you have Independent hotels with their comfy beds and thoughtful amenities waiting to tuck you in.

As you like it

Have a price you want to stick to, so you can paint the town red? Maybe, it’s all about the hotel features. Who couldn’t use a hot tub? Pick your pleasure by:

  • Hotwire Hot Rate: Grab the Independent hotel in Cape Girardeau at an absolute steal. After you book it, we’ll tell you the hotel name. You might nab that 4-star hotel for a 2-star price.
  • Price: How low can we go? Quite low in fact. Check out our prices per night, starting at $62.
  • Amenities: Grab a cocktail at the lounge and maybe wander upstairs to the rooftop terrace—all the stuff that makes a great vacay.

You’ve already done the hard part—figuring out where you want to stay. Now it’s time to use the money you saved to let the real fun begin. Underground shows? Off-beat attractions? Rooftop escapes? The choice is yours. The only thing wonderfully predictable about this trip is the Independent room you’ll be staying in.