Hotels Near
Greater South Side

Check Last Minute Greater South Side Hotel Deals

Tonight Apr 19 - Apr 20This weekend Apr 19 - Apr 21

You choose what matters — star rating, location, amenities.

We pick the perfect hotel, packed with all your must-haves.

Your hotel is revealed right after booking, and you save up to 60%!


Featured Greater South Side Hotels

Days Inn & Suites by Wyndham Des Moines Airport
Days Inn & Suites by Wyndham Des Moines Airport
2 out of 5
1901 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.2/10 Very Good! (1,104 reviews)
"Very quiet location. Easy check in and very clean"

Reviewed on Apr 12, 2024

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport
Hampton Inn Des Moines-Airport
2.5 out of 5
5001 Fleur Dr, Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.4/10 Very Good! (1,002 reviews)
"Disappointed that I was charged $50 for parking to fly."

Reviewed on Apr 18, 2024

Hampton Inn Des Moines-Airport
AmericInn by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport
2.5 out of 5
1920 Hackley Ave, Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
7.6/10 Good! (875 reviews)
"Initially we were at room 124 where the carpet was not cleaned, bathroom door did not close properly and the toilet seat was found to be shaky. It would be good if carpets and curtains were replaced."

Reviewed on Apr 16, 2024

AmericInn by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport
Quality Inn & Suites Des Moines Airport
2.5 out of 5
5231 Fleur Dr, Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7/10 Good! (764 reviews)
"Construction on road made it touchy. No motel’s fault. Girl at desk was very patient and helpful. Car Play on car map declared the property “permanently closed “ which was remedied by Choice Hotel call. Must say seeing that, was very disconcerting. It was open after their checking for me. Thank ..."

Reviewed on Apr 16, 2024

Quality Inn & Suites Des Moines Airport
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel
3 out of 5
6111 Fleur Dr, Des Moines, IA
Fully refundable
Stay at this hotel in Des Moines. Enjoy free WiFi, free parking, and breakfast. Our guests praise the helpful staff and the room service in our reviews. Popular ...
8.2/10 Very Good! (413 reviews)
"Great for kids, hot tub could use some updating"

Reviewed on Apr 15, 2024

Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel
Stoney Creek Hotel Des Moines - Johnston
Stoney Creek Hotel Des Moines - Johnston
2.5 out of 5
5291 Stoney Creek Court, Johnston, IA
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.8/10 Excellent! (1,104 reviews)
"Got an upgrade for thee same price and loved it. Will definitely be back soon. The cottages were very nice and roomy as well."

Reviewed on Apr 17, 2024

Stoney Creek Hotel Des Moines - Johnston
Hotel Fort Des Moines, Curio Collection by Hilton
Hotel Fort Des Moines, Curio Collection by Hilton
4.5 out of 5
1000 Walnut St, Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast, and room service. Our guests praise the restaurant and the helpful staff in our reviews. ...
9.4/10 Exceptional! (674 reviews)
"Unique, historic experience. Parking ramp right behind hotel, easy access to the hotel."

Reviewed on Apr 15, 2024

Hotel Fort Des Moines, Curio Collection by Hilton
Surety Hotel
Surety Hotel
4 out of 5
206 6th Ave., Des Moines, IA
Fully refundableReserve now, pay when you stay
Stay at this 4-star hotel in Des Moines. Enjoy free WiFi, 2 restaurants, and breakfast. Our guests praise the restaurant and the bar in our reviews. Popular ...
9.2/10 Wonderful! (626 reviews)
"Pet friendly!!!!"

Reviewed on Apr 14, 2024

Surety Hotel
La Quinta by Wyndham Altoona Des Moines
La Quinta by Wyndham Altoona Des Moines
2.5 out of 5
1785 11th Street NW, Altoona, IA
Fully refundableReserve now, pay when you stay
Stay at this business-friendly hotel in Altoona. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
9/10 Wonderful! (1,327 reviews)
"Great price, excellent breakfast, clean."

Reviewed on Apr 16, 2024

La Quinta by Wyndham Altoona Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
3 out of 5
5000 Merle Hay Rd, Urbandale, IA
Fully refundableReserve now, pay when you stay
Stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
6.4/10 (1,002 reviews)
"I was SUPER skeptical to book this stay based off the reviews here and the price seemed too good to be true. Hotel rooms are a bit outdated and dingy. But for the price of the room and the pool it's completely worth it! It wasnt dirty by any means. We stayed in a poolside suite with a hottub. The ..."

Reviewed on Apr 17, 2024

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Econo Lodge Inn & Suites - Des Moines/Merle Hays Road
Econo Lodge Inn & Suites - Des Moines/Merle Hays Road
2 out of 5
4755 Merle Hay Road, Des Moines, IA
Stay at this business-friendly hotel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (1,007 reviews)
"Ignore all reviews prior to March 2024. Renovated, nice, secure, modern, well lit parking and great service with a fantastic price."

Reviewed on Apr 14, 2024

Econo Lodge Inn & Suites - Des Moines/Merle Hays Road
Wildwood Lodge
Wildwood Lodge
3 out of 5
11431 Forest Ave, Clive, IA
Fully refundableReserve now, pay when you stay
Stay at this 3-star hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. Popular attractions ...
9.4/10 Exceptional! (1,355 reviews)
"Really impressed with the hotel. Very comfortable, friendly staff, clean room, nice shower! Will be making this our regular Des Moines stop!!"

Reviewed on Apr 15, 2024

Wildwood Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Greater South Side

Des Moines is a city that has a lot going on, but you have your sights set on Greater South Side. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Greater South Side has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Greater South Side hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Des Moines so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Greater South Side underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Greater South Side city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Greater South Side cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Greater South Side at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $63
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Greater South Side hotel you want, book it, and never look back. Because your great escape is ahead of you.