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21C Museum Hotel St Louis

4.5 star property

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Photo gallery for 21C Museum Hotel St Louis

Exterior
Lobby
Indoor pool
Room, 1 King Bed, Corner | In-room safe, desk, laptop workspace, blackout drapes
In-room safe, desk, laptop workspace, blackout drapes

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Bar

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • Enterprise Center
    ‪8 min walk‬
  • St. Louis Union Station
    ‪12 min walk‬
  • Busch Stadium
    ‪18 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪26 min drive‬

Room options

Loft, 2 Queen Beds

  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | In-room safe, desk, laptop workspace, blackout drapes

Deluxe Room, 1 King Bed

  • 309 sq ft
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | In-room safe, desk, laptop workspace, blackout drapes

Room (Bunk Bed)

  • Sleeps 2
  • 1 Twin Bunk Bed

View all photos for Deluxe Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Double Room, 2 Queen Beds

  • 369 sq ft
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, Accessible (Accessible)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | In-room safe, desk, laptop workspace, blackout drapes

Room, 1 King Bed, Corner

  • 326 sq ft
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout drapes

Deluxe Suite, 1 King Bed

  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout drapes

Luxury Double Room, 2 Queen Beds

  • 423 sq ft
  • Sleeps 4
  • 2 Queen Beds

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About this property

21C Museum Hotel St Louis

4.5-star hotel in Downtown West
This smoke-free hotel features an indoor pool, a restaurant, and a fitness center. WiFi in public areas is free. Additionally, a bar/lounge, a steam room, and a coffee shop/cafe are onsite. Change of towels is available on request.
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and safes. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs, and phones. Additionally, rooms include complimentary bottled water and irons/ironing boards. Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Recreational amenities at the hotel include an indoor pool, a steam room, and a fitness center.
Guests can pamper themselves by indulging in the onsite spa services. Services include massages.
In addition to an indoor pool, 21C Museum Hotel St Louis provides a steam room and a fitness center. Dining options at the hotel include a restaurant and a coffee shop/cafe. A bar/lounge is on site where guests can unwind with a drink. Public areas are equipped with complimentary wireless Internet access.

Business-related amenities at this 4.5-star property consist of a business center and meeting rooms. This luxury hotel also offers spa services, a vending machine, and concierge services. Parking is available onsite for a surcharge.

21C Museum Hotel St Louis is a smoke-free property.

Cooked-to-order breakfasts are available for a surcharge and are served each morning between 6:30 AM and 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Languages

English

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Elevator (42 inch wide door)
  • Grab bar in shower (35 inches high)
  • Handrails in stairways (36 inches high)
  • Lever door handles
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk (36 inches high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathrobes
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; Check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Cribs (infant beds) are not available

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Property Registration Number 832174967

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 783 out of 1080 reviews
Rating 8 - Good. 165 out of 1080 reviews
Rating 6 - Okay. 61 out of 1080 reviews
Rating 4 - Poor. 32 out of 1080 reviews
Rating 2 - Terrible. 39 out of 1080 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

perfect for couples

We stayed at 21C for an overnight getaway. The check in was seamless- the staff was very friendly. Our room was beautiful and clean (was missing body wash but it was quickly rectified). The robes were luxurious, a really nice touch. We enjoyed all of the amenities at the hotel; the pool, hot tub and sauna (all clean and enjoyable), the "nightcap at the museum" and the art museum as well. We had a reservation at the restaurant (best burger in town!) and went back to the bar for dessert and drinks later in the evening (I wish dessert was better). In the morning we went to the coffee shop for breakfast (so delicious!). Everything we needed was right there. The only negatives were; the pillows were not comfortable, the cups in the room for coffee were disposable and not mugs (I prefer mugs and that's what's shown on the website) and I wish parking wasn't so expensive. Overall, a really wonderful experience- we will definitely stay at the 21C again.
Stayed 1 night in Jan 2025

10/10 Excellent

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stay here instead of a conference hotel!

Lovely two-night stay at the 21c STL. Very reasonable room price, nice bar and very good restaurant, comfy "gameroom" for hanging out. Thoughtful art and interior design as you would expect from a 21c property. Yummy coffee/tea/breakfast shop.
Stayed 2 nights in Jan 2025

8/10 Good

Josh

Stayed 1 night in Jan 2025

8/10 Good

Ana Cecilia Correia

Business traveler
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
More museum than hotel, food options limited and very busy main floor and restaurant
Stayed 6 nights in Dec 2024

10/10 Excellent

Michael

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Cool spot
Stayed 2 nights in Jan 2025

10/10 Excellent

Kevin, Leawood

Traveled with partner, Traveled with pets
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
A Perfectly Curated Wes Anderson-Style Stay at 21c Museum Hotel St. Louis The 21c Museum Hotel in St. Louis is nothing short of extraordinary—a perfectly curated Wes Anderson-esque experience that feels as if you’ve stepped into a cinematic dream. From the moment we arrived, we were immersed in the hotel’s vibrant yet sophisticated aesthetic, seamlessly blending artistry and luxury. Our corner suite was a highlight, featuring impeccable design and one of the most stunning bathrooms we’ve ever seen. Every detail, from the decor to the amenities, exuded thoughtful elegance. The spacious layout and expansive views made it a true haven of relaxation. The hotel’s dedication to merging art and hospitality sets it apart. Wandering through the gallery-like spaces was a delightful experience, with each piece adding to the hotel’s unique charm. The staff was attentive and welcoming, ensuring our stay was flawless from start to finish. This was, without a doubt, one of the finest hotels we’ve ever stayed at. We are eagerly anticipating our return, this time to indulge in the duplex 21c Suite, which promises an even more extraordinary stay. For anyone seeking an unforgettable blend of art, design, and luxury, the 21c Museum Hotel St. Louis is an absolute must-visit.

10/10 Excellent

KELLIE

Stayed 1 night in Dec 2024

10/10 Excellent

Staci

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Dec 2024

8/10 Good

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

John

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
How friendly the velet parking people were. Didnt really car for it being a lane pool and how expiedia stated the rooms were sound proof when they were not. But other than that it was an amazing stay!
Stayed 2 nights in Jan 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfection!

10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!
Stayed 1 night in Jan 2025

10/10 Excellent

Patrice

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay in unique hotel

I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.
Pool area
Potatoes
Soup
Churros
Stayed 2 nights in Oct 2024

10/10 Excellent

Crystal

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Jan 2025

10/10 Excellent

Jerrod

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
One of the best hotel chains around. Amazing gallery spaces and swell rooms. Don't miss the restaurant and cafe.
Stayed 2 nights in Oct 2024

10/10 Excellent

Caroline

Liked: Cleanliness
Stayed 2 nights in Dec 2024

10/10 Excellent

Irna

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Stephan

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Alexander

Stayed 2 nights in Jan 2025

10/10 Excellent

Dimonica

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Dec 2024

10/10 Excellent

Greg Phillip Beasley

Stayed 4 nights in Dec 2024

10/10 Excellent

Madison

Liked: Staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

8/10 Good

Natalie

Stayed 2 nights in Dec 2024

8/10 Good

Raegan

Traveled with family and small children, Traveled with family
Liked: Staff & service, property conditions & facilities
Disliked: Cleanliness
Air filter in room looks like it hadn’t been changed since they built a place. Lights in room aren’t all working.
Stayed 1 night in Jan 2025

10/10 Excellent

regine

Traveled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Highly recommend!

Beautiful property! Loved the decor. The rooms we chose was large (2 beds) and comfortable. Very clean and modern. Great bar! Mason is a great bartender!
Stayed 1 night in Jan 2025