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Hotels in Seneca

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Last Minute Hot Rate® Hotel Deals in Seneca

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Choose from 1474 Seneca Hotel Deals

Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
2 out of 5
1007 George Smith Mill Rd, Anderson, SC
  • 43 min drive from Keowee Reservoir
The price is $59 per night from Apr 4 to Apr 5
$59
per night
Apr 4 - Apr 5
Stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (678 reviews)
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Reviewed on Mar 26, 2024

Days Inn by Wyndham Anderson
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $109 per night from Mar 31 to Apr 1
$109
per night
Mar 31 - Apr 1
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
9/10 Wonderful! (566 reviews)
"Was easy to check in with lakeside and our room was great. Also the restaurant was very good food and drinks. The atmosphere was nice with it sitting by the lake! Would love to stay here again"

Reviewed on Mar 24, 2024

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $98 per night from Apr 7 to Apr 8
$98
per night
Apr 7 - Apr 8
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.2/10 Wonderful! (549 reviews)
"Need a canopy at the drop off area as it was raining when we got there and everything got wet"

Reviewed on Mar 25, 2024

Tru by Hilton Seneca Clemson
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $80 per night from Mar 31 to Apr 1
$80
per night
Mar 31 - Apr 1
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
7.8/10 Good! (469 reviews)
"Its quite friendly great workers"

Reviewed on Mar 19, 2024

Quality Inn Seneca US-123
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
  • 14 min drive from Keowee Reservoir
The price is $64 per night from Apr 4 to Apr 5
$64
per night
Apr 4 - Apr 5
Stay at this business-friendly motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
6.8/10 (586 reviews)
"It really didn't matter, but I reserved a King and when I checked in, not only was there no King, there was no Queen. got two Fulls. Like I said, didn't really matter but for others that could be frustrating (especially if it was a couple)."

Reviewed on Mar 25, 2024

Days Inn by Wyndham Seneca / Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
  • 7 min drive from Keowee Reservoir
The price is $114 per night from Apr 4 to Apr 5
$114
per night
Apr 4 - Apr 5
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.2/10 Wonderful! (502 reviews)
"The trip was very nice. The weather, the people, the experiences."

Reviewed on Mar 16, 2024

Hampton Inn & Suites Seneca-Clemson Area
Best Western Seneca-Clemson
Best Western Seneca-Clemson
2.5 out of 5
511 Bypass Highway 123, Seneca, SC
  • 8 min drive from Keowee Reservoir
The price is $98 per night from Apr 9 to Apr 10
$98
per night
Apr 9 - Apr 10
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.4/10 Very Good! (509 reviews)
"Very good Breakfast ready ahead of time"

Reviewed on Mar 18, 2024

Best Western Seneca-Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $99 per night from Mar 30 to Mar 31
$99
per night
Mar 30 - Mar 31
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (1,004 reviews)
"Very friendly front desk gal and very clean hotel"

Reviewed on Mar 26, 2024

Inn @ Clemson
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Keowee Reservoir
The price is $189 per night from Apr 22 to Apr 23
$189
per night
Apr 22 - Apr 23
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast, and valet parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (228 reviews)
"Gorgeous property"

Reviewed on Mar 27, 2024

The Shepherd Hotel Downtown Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $88 per night from Apr 1 to Apr 2
$88
per night
Apr 1 - Apr 2
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (749 reviews)
"Property is in beautiful condition and well-maintained"

Reviewed on Mar 28, 2024

Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University Area
2.5 out of 5
1305 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $83 per night from Apr 9 to Apr 10
$83
per night
Apr 9 - Apr 10
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful staff ...
8/10 Very Good! (998 reviews)
Great place to stay!
"Comfort Inn & Suites is a great option for those staying in Clemson. The property is clean and is just off a main highway about a mile from Clemson University."

Reviewed on Mar 13, 2024

Comfort Inn & Suites Clemson - University Area
The Inn at Patrick Square
The Inn at Patrick Square
3.5 out of 5
115 Market Street, Clemson, SC
  • 22 min drive from Keowee Reservoir
The price is $129 per night from Apr 17 to Apr 18
$129
per night
Apr 17 - Apr 18
Stay at this 3.5-star hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
9.8/10 Exceptional! (595 reviews)
"Cute, clean, and convenient to campus."

Reviewed on Mar 25, 2024

The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Seneca

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Seneca hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Seneca.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Seneca’s 1,474 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Seneca hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Seneca. No matter your reason for visiting Seneca, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Seneca hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Seneca for as low as $59.

How many hotels are there in Seneca?

With over 1,474 hotels in Seneca, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Seneca?

Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Seneca now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Seneca right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.