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Hotels in Seneca

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Last Minute Hot Rate® Hotel Deals in Seneca

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Choose from 1482 Seneca Hotel Deals

Days Inn by Wyndham Anderson
Days Inn by Wyndham Anderson
2 out of 5
1007 George Smith Mill Rd, Anderson, SC
  • 43 min drive from Keowee Reservoir
The price is $59 per night from Apr 25 to Apr 26
$59
per night
Apr 25 - Apr 26
Stay at this business-friendly motel in Anderson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (693 reviews)
"Beds too high and prefer carpeted floors"

Reviewed on Apr 15, 2024

Days Inn by Wyndham Anderson
Lakeside Lodge Clemson
Lakeside Lodge Clemson
2.5 out of 5
13500 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $109 per night from Apr 21 to Apr 22
$109
per night
Apr 21 - Apr 22
Stay at this hotel in Seneca. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the pool and the restaurant in our reviews. Popular attractions ...
8.8/10 Excellent! (578 reviews)
"This was an excellent hotel. We would stay here again!"

Reviewed on Apr 6, 2024

Lakeside Lodge Clemson
Tru by Hilton Seneca Clemson
Tru by Hilton Seneca Clemson
2.5 out of 5
13050 Clemson Blvd, Seneca, SC
  • 11 min drive from Keowee Reservoir
The price is $98 per night from Apr 28 to Apr 29
$98
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.2/10 Wonderful! (561 reviews)
"Really close to Clemson University campus. Newer property that has been maintained very well."

Reviewed on Apr 15, 2024

Tru by Hilton Seneca Clemson
Quality Inn Seneca US-123
Quality Inn Seneca US-123
2.5 out of 5
226 Hi Tech Rd, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $85 per night from Apr 25 to Apr 26
$85
per night
Apr 25 - Apr 26
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. Popular ...
7.8/10 Good! (476 reviews)
"Close to Memorial Stadium as well as resturants"

Reviewed on Apr 11, 2024

Quality Inn Seneca US-123
Days Inn by Wyndham Seneca / Clemson Area
Days Inn by Wyndham Seneca / Clemson Area
2 out of 5
11015 N Radio Station Rd, Seneca, SC
  • 14 min drive from Keowee Reservoir
The price is $68 per night from Apr 26 to Apr 27
$68
per night
Apr 26 - Apr 27
Stay at this business-friendly motel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
6.8/10 (593 reviews)
"Hotel staff was nice."

Reviewed on Apr 15, 2024

Days Inn by Wyndham Seneca / Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
Hampton Inn & Suites Seneca-Clemson Area
2.5 out of 5
1011 East North 1st Street, Seneca, SC
  • 7 min drive from Keowee Reservoir
The price is $115 per night from Apr 25 to Apr 26
$115
per night
Apr 25 - Apr 26
Stay at this business-friendly hotel in Seneca. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our ...
9.4/10 Exceptional! (509 reviews)
"Very nice clean hotel with a great breakfast. Would definitely stay there again while we were visiting clemson university."

Reviewed on Apr 15, 2024

Hampton Inn & Suites Seneca-Clemson Area
Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 out of 5
800 BYPASS 123, Seneca, SC
  • 10 min drive from Keowee Reservoir
The price is $129 per night from Apr 22 to Apr 23
$129
per night
Apr 22 - Apr 23
Stay at this business-friendly hotel in Seneca. Enjoy free parking, a fitness center, and a 24-hour front desk. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (100 reviews)
"Very nice property. Staff was exceptional. Highly recommend staying there."

Reviewed on Apr 12, 2024

Fairfield Inn & Suites Seneca Clemson Univ Area
The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown Clemson
4 out of 5
110 Sloan St, Clemson, SC
  • 15 min drive from Keowee Reservoir
The price is $169 per night from May 12 to May 13
$169
per night
May 12 - May 13
Stay at this 4-star hotel in Clemson. Enjoy free WiFi, breakfast, and valet parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
9.8/10 Exceptional! (247 reviews)
"Check in staff was amazing,patient, offering restaurant suggestions and assistance in our college tour set up and arrival. Beautiful hotel with amazing space!"

Reviewed on Apr 16, 2024

The Shepherd Hotel Downtown Clemson
Inn @ Clemson
Inn @ Clemson
2.5 out of 5
1303 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $99 per night from Apr 20 to Apr 21
$99
per night
Apr 20 - Apr 21
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8/10 Very Good! (1,001 reviews)
Weekend collage visit
"Weekend visit with our Clemson student"

Reviewed on Apr 15, 2024

Inn @ Clemson
Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference Center
2.5 out of 5
1310 Tiger Blvd, Clemson, SC
  • 16 min drive from Keowee Reservoir
The price is $93 per night from Apr 28 to Apr 29
$93
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (765 reviews)
Very spacious
"Everything was great except front person told us wrong information about breakfast time, and missed breakfast."

Reviewed on Apr 17, 2024

Best Western Plus Clemson Hotel & Conference Center
Holiday Inn Express & Suites Clemson, an IHG Hotel
Holiday Inn Express & Suites Clemson, an IHG Hotel
2.5 out of 5
1381 Tiger Blvd, Clemson, SC
  • 17 min drive from Keowee Reservoir
The price is $101 per night from Apr 28 to Apr 29
$101
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Clemson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (773 reviews)
"the hotel is very clean and close to everything"

Reviewed on Apr 15, 2024

Holiday Inn Express & Suites Clemson, an IHG Hotel
The Inn at Patrick Square
The Inn at Patrick Square
3.5 out of 5
115 Market Street, Clemson, SC
  • 22 min drive from Keowee Reservoir
The price is $129 per night from May 1 to May 2
$129
per night
May 1 - May 2
Stay at this 3.5-star hotel in Clemson. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
9.8/10 Exceptional! (601 reviews)
"Quaint and quiet. Conveniently located close Clemson University."

Reviewed on Apr 17, 2024

The Inn at Patrick Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Seneca

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Seneca hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Seneca.

Choosing the right hotel in South Carolina has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Seneca’s 1,482 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $59. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Seneca hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Seneca. No matter your reason for visiting Seneca, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Seneca hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Seneca for as low as $59.

How many hotels are there in Seneca?

With over 1,482 hotels in Seneca, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $59.

How to find cheap car rentals in Seneca?

Finding a cheap car rental deal in Seneca is as easy as scoring cheap hotels in Seneca. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Seneca now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Seneca right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.