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  1. SpringHill Suites by Marriott Orlando Lake Nona

    Lake Nona Medical City
    Breakfast included
    4.7 out of 5 Exceptional (56 reviews)
    We have 5 left at
    Price is $179
    per night
    $201 total
    Includes taxes & fees
    More information about SpringHill Suites by Marriott Orlando Lake Nona, Opens in a new window
  2. Courtyard Orlando Lake Nona

    Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.7 out of 5 Exceptional (373 reviews)
    We have 5 left at
    Price is $199
    per night
    $224 total
    Includes taxes & fees
    More information about Courtyard Orlando Lake Nona, Opens in a new window
  3. Residence Inn Orlando Lake Nona

    Lake Nona Medical City
    Breakfast included
    4.7 out of 5 Exceptional (208 reviews)
    We have 5 left at
    Price is $179
    per night
    $201 total
    Includes taxes & fees
    More information about Residence Inn Orlando Lake Nona, Opens in a new window
  4. Unlock up to 40% off select Hotels in Lake Nona Medical City, Florida, United States of America

    Unlock up to 40% off select Hotels in Lake Nona Medical City, Florida, United States of America

    Get deep discounts on Hotwire Hot Rate Hotels
  5. Cambria Hotel Orlando Airport

    Orlando, 6.93 mi from Lake Nona Medical City
    4.5 out of 5 Wonderful (164 reviews)
    Price is $127
    per night
    $142 total
    Includes taxes & fees
    More information about Cambria Hotel Orlando Airport, Opens in a new window
  6. Hyatt Regency Orlando International Airport

    Orlando, 4.78 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.6 out of 5 Wonderful (2,949 reviews)
    We have 1 left at
    Price was $239Price is now $219
    per night
    $246 total
    Includes taxes & fees
    More information about Hyatt Regency Orlando International Airport, Opens in a new window
  7. Wyndham Garden Orlando Airport

    Orlando, 7.39 mi from Lake Nona Medical City
    Price is $123
    per night
    $137 total
    Includes taxes & fees
    More information about Wyndham Garden Orlando Airport, Opens in a new window
  8. Holiday Inn Express & Suites Orlando - Lake Nona Area, an IHG Hotel

    Lake Hart, 2.4 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.5 out of 5 Wonderful (219 reviews)
    We have 1 left at
    Price was $132Price is now $125
    per night
    $141 total
    Includes taxes & fees
    More information about Holiday Inn Express & Suites Orlando - Lake Nona Area, an IHG Hotel, Opens in a new window
  9. Garnet Inn & Suites

    Orlando, 9.27 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    Price is $71
    per night
    $80 total
    Includes taxes & fees
    More information about Garnet Inn & Suites, Opens in a new window
  10. Florida Hotel & Conference Center in the Florida Mall

    Orlando, 9.02 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.5 out of 5 Wonderful (1,235 reviews)
    20% off
    Price was $186Price is now $149
    per night
    $189 total
    Includes taxes & fees
    More information about Florida Hotel & Conference Center in the Florida Mall, Opens in a new window
  11. Stayable Suites Kissimmee

    Kissimmee, 7.38 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    3.5 out of 5 Good (1,000 reviews)
    Price was $86Price is now $65
    per night
    $74 total
    Includes taxes & fees
    More information about Stayable Suites Kissimmee, Opens in a new window
  12. La Quinta Inn & Suites by Wyndham Orlando Airport North

    Orlando, 6.74 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.1 out of 5 Very Good (2,352 reviews)
    We have 1 left at
    Price is $97
    per night
    $109 total
    Includes taxes & fees
    More information about La Quinta Inn & Suites by Wyndham Orlando Airport North, Opens in a new window
  13. Wingate by Wyndham - Orlando International Airport

    Orlando, 6.86 mi from Lake Nona Medical City
    Breakfast included
    4.2 out of 5 Very Good (2,071 reviews)
    We have 6 left at
    Price was $122Price is now $102
    per night
    $114 total
    Includes taxes & fees
    More information about Wingate by Wyndham - Orlando International Airport, Opens in a new window
  14. The Ritz-Carlton Orlando, Grande Lakes

    Orlando, 9.93 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.6 out of 5 Wonderful (1,000 reviews)
    We have 5 left at
    Price was $499Price is now $399
    per night
    $489 total
    Includes taxes & fees
    More information about The Ritz-Carlton Orlando, Grande Lakes, Opens in a new window
  15. Flamingo Express Hotel

    Kissimmee, 7.23 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    3.7 out of 5 Good (779 reviews)
    10% off
    Price was $63Price is now $57
    per night
    $64 total
    Includes taxes & fees
    More information about Flamingo Express Hotel, Opens in a new window
  16. Best Western Airport Inn & Suites

    Orlando, 7.59 mi from Lake Nona Medical City
    3.8 out of 5 Good (1,583 reviews)
    We have 5 left at
    Price was $124Price is now $93
    per night
    $104 total
    Includes taxes & fees
    More information about Best Western Airport Inn & Suites, Opens in a new window
  17. Country Inn & Suites by Radisson, Orlando Airport, FL

    Orlando, 6.81 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    3.9 out of 5 Good (2,783 reviews)
    We have 1 left at 12% off at
    Price was $129Price is now $114
    per night
    $128 total
    Includes taxes & fees
    More information about Country Inn & Suites by Radisson, Orlando Airport, FL, Opens in a new window
  18. Holiday Inn Orlando International Airport, an IHG Hotel

    Orlando, 6.72 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.0 out of 5 Very Good (953 reviews)
    We have 3 left at
    Price was $140Price is now $134
    per night
    $151 total
    Includes taxes & fees
    More information about Holiday Inn Orlando International Airport, an IHG Hotel, Opens in a new window
  19. Hampton Inn Orlando-International Airport

    Orlando, 6.71 mi from Lake Nona Medical City
    Breakfast included
    4.4 out of 5 Excellent (998 reviews)
    We have 4 left at
    Price was $195Price is now $152
    per night
    $171 total
    Includes taxes & fees
    More information about Hampton Inn Orlando-International Airport, Opens in a new window
  20. Kapp and Kappy B&B

    Historic Downtown Kissimmee, 9.87 mi from Lake Nona Medical City
    Fully refundable
    Reserve now, pay later
    4.8 out of 5 Exceptional (60 reviews)
    We have 1 left at
    Price is $209
    per night
    $237 total
    Includes taxes & fees
    More information about Kapp and Kappy B&B, Opens in a new window
  21. DoubleTree by Hilton Orlando Airport

    Orlando, 6.98 mi from Lake Nona Medical City
    4.1 out of 5 Very Good (1,005 reviews)
    We have 6 left at 15% off at
    Price was $152Price is now $129
    per night
    $145 total
    Includes taxes & fees
    More information about DoubleTree by Hilton Orlando Airport, Opens in a new window