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Hotels in Florida Keys

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Last Minute Hot Rate® Hotel Deals in Florida Keys

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Choose from 7979 Florida Keys Hotel Deals

Coconut Cay Resort & Marina
Coconut Cay Resort & Marina
2 out of 5
7196 Overseas Highway, Marathon, FL
  • 2 hours drive from Duval Street
The price is $139 per night from May 12 to May 13
$139
per night
May 12 - May 13
Stay at this hotel in Marathon. Enjoy free WiFi, free parking, and a marina. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...
8.4/10 Very Good! (1,001 reviews)
"Great property for price. Awsome tonl have access to bikes,paddle boards,kayacks, fishing equipment."

Reviewed on May 9, 2024

Coconut Cay Resort & Marina
Chesapeake Beach Resort
Chesapeake Beach Resort
2.5 out of 5
83409 Overseas Hwy, Islamorada, FL
  • 3 hours drive from Duval Street
The price is $199 per night from May 19 to May 20
$199
per night
May 19 - May 20
Book a stay at this beach hotel in Islamorada. Enjoy 2 outdoor pools, a private beach, and a 24-hour front desk. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,310 reviews)
"Beautiful rooms and super clean and great condition of beds and decoration."

Reviewed on May 10, 2024

Chesapeake Beach Resort
Cheeca Lodge & Spa
Cheeca Lodge & Spa
4 out of 5
81801 Overseas Highway, Mile Marker 82, Marker 82, Islamorada, FL
  • 3 hours drive from Duval Street
The price is $239 per night from May 12 to May 13
$239
per night
May 12 - May 13
Book a stay at this beach resort in Islamorada. Enjoy free parking, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff ...
8.8/10 Excellent! (1,004 reviews)
"Great place overall. Rooms that connect bleed noise through the door badly"

Reviewed on May 7, 2024

Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa
Isla Bella Beach Resort & Spa
5 out of 5
1 Knights Key Boulevard, MM 47, Marathon, FL
  • 2 hours drive from Duval Street
The price is $339 per night from May 19 to May 20
$339
per night
May 19 - May 20
Stay at this 5-star luxury hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the pool and the helpful staff in our ...
8.8/10 Excellent! (1,000 reviews)
"The front desk staff at this resort are quite possibly the rudest I have experienced in my two week trip across Florida. On both check in and check out nobody offered to take our luggage to and from our room. We had a welcome bowl of cheese and fruit, this was then left in the room and not cleared ..."

Reviewed on May 7, 2024

Isla Bella Beach Resort & Spa
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Baker's Cay Resort Key Largo, Curio Collection by Hilton
4 out of 5
97000 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $208 per night from May 22 to May 23
$208
per night
May 22 - May 23
Book a stay at this beach hotel in Key Largo. Enjoy 2 outdoor pools, 2 restaurants, and a private beach. Our guests praise the pool and the helpful staff in ...
8.6/10 Excellent! (1,002 reviews)
"Mannie was the best!"

Reviewed on May 10, 2024

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Lime Tree Bay Resort
Lime Tree Bay Resort
3.5 out of 5
68500 Overseas Hwy, Long Key, FL
  • 3 hours drive from Duval Street
The price is $159 per night from May 12 to May 13
$159
per night
May 12 - May 13
Stay at this 3.5-star beach resort in Long Key. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (1,004 reviews)
Perfect resort
"Excellent facilities - perfect for learning how to paddleboard. Saw a turtle from the paddleboard, a nurse shark and lots of fish. Really nice rooms."

Reviewed on May 9, 2024

Lime Tree Bay Resort
Marina Del Mar Resort and Marina
Marina Del Mar Resort and Marina
2.5 out of 5
527 Caribbean Drive, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $144 per night from May 12 to May 13
$144
per night
May 12 - May 13
Stay at this hotel in Key Largo. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the pool and the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (1,163 reviews)
Keys vibe, takin' in stride
"Went for a last-minute girls weekend and it was great. Very convenient to local spots, nice walkway along the canal, extra perk of having access to another hotel pool, and relatively friendly staff. The room was comfortable and had a lovely sitting area outside our door on the balcony."

Reviewed on May 7, 2024

Marina Del Mar Resort and Marina
Faro Blanco Resort & Yacht Club
Faro Blanco Resort & Yacht Club
4 out of 5
1996 Overseas Highway, Marathon, FL
  • 2 hours drive from Duval Street
The price is $204 per night from May 19 to May 20
$204
per night
May 19 - May 20
Stay at this 4-star family-friendly hotel in Marathon. Enjoy free WiFi, 2 outdoor pools, and 2 restaurants. Our guests praise the pool and the restaurant in ...
8.8/10 Excellent! (1,454 reviews)
"Personnel very nice and friendly. Excellent food in restaurant"

Reviewed on May 6, 2024

Faro Blanco Resort & Yacht Club
Bayside Inn Key Largo
Bayside Inn Key Largo
3 out of 5
99490 Overseas Hwy, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $154 per night from May 16 to May 17
$154
per night
May 16 - May 17
Book a stay at this beach hotel in Key Largo. Enjoy free WiFi, a private beach, and a 24-hour fitness center. Our guests praise the pool and the helpful staff ...
8.6/10 Excellent! (1,232 reviews)
"The rooms were very pretty and great for the night! Amazing Italian restaurant right next door"

Reviewed on May 8, 2024

Bayside Inn Key Largo
Hawks Cay Resort
Hawks Cay Resort
4 out of 5
61 Hawks Cay Blvd, Marathon, FL
  • 2 hours drive from Duval Street
The price is $299 per night from May 12 to May 13
$299
per night
May 12 - May 13
Book a stay at this beach hotel in Marathon. Enjoy free WiFi, 5 outdoor pools, and a full-service spa. Our guests praise the clean rooms and the family amenities ...
7.8/10 Good! (1,001 reviews)
"nice"

Reviewed on May 7, 2024

Hawks Cay Resort
Aqua Lodge Rentals At Coconut Cay
Aqua Lodge Rentals At Coconut Cay
3.5 out of 5
7200 Aviation Blvd, Marathon, FL
  • 2 hours drive from Duval Street
The price is $179 per night from May 19 to May 20
$179
per night
May 19 - May 20
Stay at this 3.5-star vacation home in Marathon. Enjoy free WiFi, free parking, and daily housekeeping. Our guests praise the pool and the helpful staff in our ...
9.6/10 Exceptional! (101 reviews)
"Very clean, comfortable and relaxing."

Reviewed on Apr 26, 2024

Aqua Lodge Rentals At Coconut Cay
Playa Largo Resort & Spa, Autograph Collection
Playa Largo Resort & Spa, Autograph Collection
4.5 out of 5
97450 Overseas Highway, Key Largo, FL
  • 4 hours drive from Duval Street
The price is $429 per night from May 12 to May 13
$429
per night
May 12 - May 13
Stay at this 4.5-star luxury resort in Key Largo. Enjoy free WiFi, a full-service spa, and 3 restaurants. Our guests praise the pool and the helpful staff in ...
8.8/10 Excellent! (1,002 reviews)
"Nice overall"

Reviewed on May 8, 2024

Playa Largo Resort & Spa, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

HOTW-Hotel-Deals-726-959@2x.jpg (1918×258)*Savings based on Hot Rate® hotel bookings as compared with the lowest published rates found on leading retail travel sites. Hot Rates are different from retail rates. With Hot Rates you enter the date, location and star rating. Hotel revealed only after booking. All bookings final.

Find cheap hotels in Florida Keys

You’re not an average traveler—and Hotwire knows it. Your wanderlust takes you off the beaten path to discover unique adventures and every travel destination’s lesser-known tourist scenes. Hotwire has the hookup! Book your Florida Keys hotel with Hotwire to complete your one-of-a-kind travel checklist.

For you, intrepid voyager, Hotwire has a large selection of the best hotels in Florida Keys.

Choosing the right hotel in has everything to do with the way you want your trip to go. If you’ve scribbled a few obscure destinations on your itinerary, you probably already have a good sense of how your getaway is taking shape. Lean into that by booking one of Florida Keys’s 7,979 hotels. Choose the one that best catches your trip’s tourist drift.

If you’re traveling during the week for business, Hotwire can score you a luxury hotel for as low as $111. In town for pleasure? Hotwire still has you covered. If you’re in the mood for a quick last-minute weekend getaway or spa retreat, you can get up to 60% Florida Keys hotel deals at the last minute.

While traveling, where you stay plays a major role in your overall vacation enjoyment. Choosing the right hotel is just as important as making sure you book the right flight and car rental. If you’re traveling with family or friends, you may need to book a hotel with connecting rooms. If you enjoy an elegant and relaxing hotel ambiance, opt for one of Hotwire’s luxury hotels in Florida Keys. No matter your reason for visiting Florida Keys, with Hotwire’s large selection of hotels in the area, you’re sure to book a hotel that meets all your accommodation needs.

Frequently Asked Questions About Florida Keys hotels

Where can I find the best last-minute travel deals?

If you’re traveling in the spirit of spontaneity, you’ll love the idea of leaving your exact hotel choice up to chance. With Hotwire Hot Rates, you can save up to 60% off your next flight, hotel, or car rental. Just plug in your general preferences and let Hotwire choose last-minute hotel deals in Florida Keys for as low as $111.

How many hotels are there in Florida Keys?

With over 7,979 hotels in Florida Keys, you’re sure to find one that best matches your travel mood. When you book with Hotwire, you can score a stellar home away from home for as low as $111.

How to find cheap car rentals in Florida Keys?

Finding a cheap car rental deal in Florida Keys is as easy as scoring cheap hotels in Florida Keys. Hotwire partners with top-of-the-line car rental companies to bring you a large selection of affordable options. Whether you’re in need of a large SUV for the entire family or a more compact but stylish vehicle, Hotwire has you covered. You can even save up to 60% off a car rental deal if you book a Hotwire Hot Rate at the last minute.

Is it safe to travel to Florida Keys now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to Florida Keys right now?” When it’s time to book your getaway, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.